New generation of
dynamic medicines

Designed for greater precision
and control after administration

Senti Bio is pioneering cell and gene therapies designed to give clinicians greater control over therapeutic activity after administration. Our proprietary Regulator Dial™ technology uses oral medications to regulate therapeutic gene expression, with the potential to improve safety and optimize treatment effects.

Through research collaborations, we are exploring applications in gene therapy for Rett syndrome and armored tumor-infiltrating lymphocyte (TIL) therapies for solid tumors. These research-stage programs seek to address difficult-to-treat diseases by controlling how and when powerful genetic medicines act inside the body.

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Powerful therapies need precise control

The potential of cell and gene therapies depends on more than delivering a treatment. The level and timing of biological activity matter. Insufficient activity may limit benefit, while excessive activity may cause toxicity, making precise control a critical challenge for the next generation of medicines. Our Regulator Dial™ technology is designed to provide that control, enabling therapeutic activity to be adjusted after administration.

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“The field of synthetic biology has evolved rapidly over the past few decades. We believe that we are uniquely positioned to harness its potential to drive significant advances in medicine.”

Tim Lu, MD, PhD
Co-Founder and CEO, Senti Bio

Be a part of the world-class team at Senti Bio and help engineer what’s next.

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