Presentations & Publications

May 2024

Engineered IMiD Regulated Synthetic Transcriptional Switch for Controlled and Dose-Responsive Expression of Therapeutic Payload within FDA-Approved Drug Doses

ASGCT Annual Meeting
Rebecca Cottman, Myles MacEachern, Michelle Hung, Andrew Banicki, Mengxi Tian, Chen-Ting Lee, Assen Roguev, Chew-Li Soh, Conor McAuliffe, Mark Tomishima, Raghav Kannan, Chandra Verma, Timothy K. Lu, Russell Gordley, Philip Lee

October 2023

Small-molecule regulated safety switch for improved safety of CAR cell therapies in the brain

SITC Annual Meeting
Rebecca T. Cottman, Vanessa Johnson, Michelle Hung, Yin Yin Chong, Eren Chu, Assen Roguev, Marcus Gainer, Joseph Sperling, Monika Avina, Brett Kiedaisch, Raghav Kannan, Chandra Verma, Chew-Li Soh, Conor McAuliffe, Mark Tomishima, Russell M. Gordley, Timothy K. Lu, and Philip Lee

May 2023

Engineering a Gene Circuit-Enabled Cell Therapy with a Tamoxifen Regulated Safety Switch for Inducible Cell Death in Human Pluripotent Stem Cells and their Derivatives

ASGCT Annual Meeting
Chew-Li Soh, Rebecca Cottman, Conor McAuliffe, Vanessa Johnson, Michelle Hung, Yin Yin Chong, Noah Jacobs-Rebhun, Cloe Grace, Jeffrey Levin, Tackla Winston, Mark Ebel, Eren Chu, Assen Roguev, Russell Gordley, Tim Lu, Mark Tomishima

May 2023

Engineering pharmacologically relevant, FDA-approved small-molecule-regulated gene circuits for therapeutic applications in the brain

ASGCT Annual Meeting
Rebecca Cottman, Vanessa Johnson, Michelle Hung, Yin Yin Chong, Andrew Banicki, Mengxi Tian, Chen -Ting Lee, Eren Chu, Assen Roguev, Monika Avina, Alex Danza, Brett Kiedaisch, Raghav Kannan, Chandra Verma, Chew -Li Soh, Conor McAuliffe, Mark Tomishima, Russell Gordley, Gary Lee, Tim Lu

May 2022

Multi-Arming and Regulator Dial Gene Circuits to Address Key Disease Challenges in HCC

ASGCT Annual Meeting
Marcela Guzman Ayala, Michelle Hung, Poornima Ramkumar, Deepika Kaveri, Elizabeth Leiner, Priscilla Wong, Ronni Ponek, Brett Kiedaisch, Wesley Gorman, Russell Gordley, Rebecca Cottman, Kelly Lee, Allison Drain, Ahmad S Khalil, Gary Lee

May 2021

Small-molecule-regulated Gene Circuit for Controlling Cytokine Expression in Cell Therapies

ASGCT Annual Meeting
Michelle Hung, Divya Israni, Huishan Li, Yin Yin Chong, Poornima Ramkumar , Allison Drain, Allison Quach, Mengxi Tian, Rishi Savur, Niran Almudhfar, Chen Ting Lee, Abla Bakir, Edwin Cruz, Carmina Blanco, Travis Wood, Mario Lorente, Brandon Lee, Brett Kiedaisch, Russell M. Gordley, Marcela Guzman Ayala, Ahmad Khalil, Gary Lee, Tim Lu